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(5R)-carbapenem carboxylate biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
H+ + L-pyrroline-5-carboxylate + malonyl-CoA + H2O <=> (2S,5S)-5-carboxymethylproline + CoA + CO2 2.3.1.226 carboxymethylproline synthase

electron-transfer_quinone + L-proline <=> electron-transfer_quinol + H+ + L-pyrroline-5-carboxylate 1.5.5.2 proline dehydrogenase

(3R,5S)-carbapenam-3-carboxylate + acceptor <=> (5R)-carbapen-2-em-3-carboxylate + reduced_acceptor not assigned

(3S,5S)-carbapenam_3-carboxylate + 2-oxoglutarate + O2 <=> (5R)-carbapen-2-em-3-carboxylate + succinate + CO2 + H2O 1.14.20
1.14.20.3 (5R)-carbapenem-3-carboxylate synthase


(3S,5S)-carbapenam_3-carboxylate <=> (3R,5S)-carbapenam-3-carboxylate not assigned

(2S,5S)-5-carboxymethylproline + ATP <=> H+ + (3S,5S)-carbapenam_3-carboxylate + AMP + diphosphate 6.3.3.6 carbapenam-3-carboxylate synthase

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